In the quest for medical advice, many turn to ChatGPT, the chatbot from OpenAI. But is it truly a reliable virtual doctor or a mischievous meddler? Join us as we explore the humorous side of ChatGPT’s medical prowess and navigate the fine line between accurate answers and playful misinformation. We sit down with Isaac Kohane, an expert in biomedical informatics, as he shares his experiences testing GPT-4 and raises important questions about AI’s role in healthcare. Get ready for a hilarious and thought-provoking journey into the world of AI medicine.